Search results for "Prothrombin gene"

showing 2 items of 2 documents

Factor V Leiden and prothrombin gene mutation in inflammatory bowel disease in a Mediterranean area.

2001

Abstract Background. Thromboembolism has been reported to be associated with inflammatory bowel disease. Aim. To evaluate the association of factor V Leiden and prothrombin gene mutation with inflammatory bowel disease in a population of patients with thromboembolic events and inflammatory bowel disease and in a control population of patients with inflammatory bowel disease without thromboembolic events. Patients and methods. A series of 18 patients with inflammatory bowel disease and a history of arterial or venous thrombosis and 45 patients with inflammatory bowel disease without thromboembolic events were evaluated for the presence of factor V Leiden and prothrombin gene mutation. Freque…

Malemedicine.medical_specialtyPathologyProthrombin gene mutationPopulationGene mutationGastroenterologyInflammatory bowel diseaseCrohn Diseasehemic and lymphatic diseasesInternal medicineThromboembolismFactor V LeidenmedicinePrevalenceHumansPoint Mutationeducationeducation.field_of_studyHepatologybusiness.industryMediterranean RegionGastroenterologyFactor VMiddle Agedmedicine.diseaseVenous thrombosisMediterranean areaColitis UlcerativeFemaleProthrombinFactor V Leiden mutationbusinessDigestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
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Comparación de las frecuencias de los alelos factor V Leiden (G1691A) y protrombina-G20210A entre pacientes con trombosis venosa profunda y población…

2006

Background: Factor V leiden and the -G20210A variant of prothrombin gene are associated to a higher risk of deep venous thrombosis. Aim: To assess the frequency of factor V Leiden (G1691A) and prothrombin -G20210A alleles in patients with deep venous thrombosis (DVT) and in the general population from Spain. Material and methods: Factor V Leiden (g1691a) and prothrombin-g20210a alleles were genotyped in 493 individuals from the Spanish general populations and in 131 patients with DVT. The presence of DVT was confirmed by phlebography. Allelic frequencies and the DVT risk associated with these variants were estimated. Results: Allelic frequencies for the factor V Leiden (G1691A) allele were …

medicine.medical_specialtyPopulationGastroenterologyInternal medicinehemic and lymphatic diseasesGenotypeG20210AVenous thrombosismedicineFactor V Leidencardiovascular diseasesAlleleeducationAlleleseducation.field_of_studyFactor V Leidenbusiness.industryGeneral MedicineOdds ratiomedicine.diseaseConfidence intervalSurgeryVenous thrombosisProthrombin geneProthrombin G20210Abusiness
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